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Cancer of the Anal Canal: AJCC TNM staging system of the Anal Canal

    • The AJCC TNM staging system uses three basic descriptors that are then grouped into stage categories.
    • The first component is “T”, which describes the extent of the primary tumor
    • The next component is “N”, which describes the absence or presence and extent of regional lymph node metastasis
    • The third component is “M”, which describes the absence or presence of distant metastasis
    • The final stage groupings (determined by the different permutations of “T”, “N”, and “M”) range from stage 0 through stage IV