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Hepatocellular carcinoma: the Okuda classification

    • To develop a simple practical staging system to elucidate the natural history and prognosis of hepatocellular cancer
    • The classification is applied retrospectively to 850 patients with hepatocellular carcinoma
    • Median survival of patients who underwent hepatic resection in stage I was 26 months and in stage II 12 months
    • Stage I patients are candidates for surgical therapy
    • Stage III are usually treated nonsurgically
    • Survival of syage II patients is highly variable